Mekanismen för squalenoxidation ligger i att dess låga joniseringströskelperiod kan donera eller ta emot elektroner utan att skada molekylstrukturen hos celler, och squalen kan avsluta kedjereaktionen av hydroperoxider i lipidperoxidationsvägen. Studies have shown that the peroxidation of sebum is mainly caused by singlet oxygen, and the singlet oxygen quenching rate constant of squalene in human sebum is much larger than that of other lipids in human skin. utrotningskonstant. However, it should be noted that although squalene can block lipid peroxidation, the products of squalene, such as unsaturated fatty acids, also have an irritating effect on the skin.
Squalen peroxid kan spela en viktig roll i patogenesen av akne. In animal experimental models, it has been established that squalene monoperoxide is highly comedogenic, and the content of squalene peroxide gradually increases under UV irradiation. Therefore, it is suggested that acne patients should pay attention to sun protection, and sunscreens can avoid squalene peroxidation at physiological concentrations caused by ultraviolet rays.
Hudanalysatorkan användas för att upptäcka effekten av solkräm. UV -bilden visas mörkblå om kemisk solskyddsmedel appliceras; Om fysisk solskyddsmedel appliceras är bilden reflekterande, liknande fluorescerande rest.
Posttid: april-29-2022
